{"id":14851,"date":"2022-08-30T14:01:10","date_gmt":"2022-08-30T14:01:10","guid":{"rendered":"https:\/\/solongevitypro.com\/?p=14851"},"modified":"2023-08-19T17:20:31","modified_gmt":"2023-08-19T17:20:31","slug":"the-4-molecules-of-longevity","status":"publish","type":"post","link":"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/","title":{"rendered":"The 4 Molecules of Longevity"},"content":{"rendered":"
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Allies against latent chronic inflammation<\/h3>\n<\/div>\n
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Resveratrol<\/strong>\u00a0and\u00a0polydatin<\/strong>,\u00a0glutathione<\/strong>\u00a0and\u00a0NAD+<\/strong>: four molecules found in different foods that are the friends of our health. Their \u201csuperpower\u201d? In a nutshell, promoting\u00a0healthy aging<\/strong>\u00a0by countering\u00a0chronic latent inflammation<\/strong>\u00a0related to many diseases. Today we launch a series of articles to learn more about them.<\/article>\n<\/div>\n<\/div>\n
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Resveratrol and polydatin<\/h3>\n<\/div>\n
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Resveratrol<\/strong>\u00a0and\u00a0polydatin<\/strong>\u00a0are\u00a0antioxidant<\/strong>\u00a0and\u00a0anti-inflammatory<\/strong>\u00a0molecules, but they also appear to have\u00a0antiviral<\/strong>\u00a0action, capable of interfering with infection by the\u00a0Sars-Cov-2<\/strong>\u00a0coronavirus and limiting its replication in nasal epithelium cells. Resveratrol is a non-flavonoid phenol found in many foods, e.g., grapes, and has been used for years for its properties that exert an antiaging effect on our bodies.\u00a0Polydatin<\/strong>\u00a0is a precursor of resveratrol and is able to improve the functioning of\u00a0mitochondria<\/strong>\u00a0(the \u2018energy\u2019 powerhouses of cells) by modulating the action of sirtuins, a group of 7 proteins critical for survival.<\/article>\n<\/div>\n<\/div>\n
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Glutathione<\/h3>\n<\/div>\n
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Glutathione<\/strong>\u00a0is one of the most powerful natural antioxidants in our bodies. It plays a central role in\u00a0\u201cdetoxification\u201d reactions<\/strong>\u00a0(by which toxins, both those produced by our bodies and those from outside, such as from drugs and food additives, are eliminated) and in\u00a0tissue repair<\/strong>, and it supports the\u00a0immune system<\/strong>. As we age, its levels decline, but it can be restored through adequate supplementation of its precursors:\u00a0glutamine<\/strong>,\u00a0cysteine<\/strong>, and\u00a0glycine<\/strong>.<\/article>\n<\/div>\n<\/div>\n
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NAD+<\/h3>\n<\/div>\n
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NAD+<\/strong>\u00a0is also strongly involved in cellular metabolism and aging. The presence of high levels of this molecule in the body, in fact, contributes to the activation of\u00a0sirtuins<\/strong>, which specifically use NAD+ to carry out their functions. As is the case with glutathione, it has been found that as we age, NAD+ tends to decline. At age 70 there is up to 40 percent less of it than at age 40. Again, however, its levels can be restored through supplementation of its precursors, for example,\u00a0nicotinamide (NAM)<\/strong>.As is often the case, using precursors brings advantages because it increases\u00a0bioavailability<\/strong>, that is, the fraction of a substance that can actually be used by the body for its physiological functions. In the case of NAD+, specifically, the molecule is too large to be absorbed by cells in the intestine, while its precursors are smaller, or there are specific transport mechanisms for their assimilation.We have devoted in-depth coverage to each of these molecules in the articles linked below on this page. You will then discover why NAD+, glutathione, polydatin and resveratrol, along with other important antioxidant molecules, are the focus of SoLongevity\u2019s research and the basis of the patents (GluReNAD<\/a>\u00a0(in Italian) and\u00a0GluRes<\/a>) for the\u00a0CellFasting<\/a>\u00a0and\u00a0NeuroProtection<\/a>\u00a0nutraceuticals.<\/article>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Resveratrol, polydatin, glutathione, and NAD+ are four of the so-called \u201clongevity molecules\u201d on which research has long focused. In a series of four articles we explain what they are and how they work.<\/p>\n","protected":false},"author":1,"featured_media":323,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[158],"tags":[168,171],"class_list":["post-14851","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","tag-nutraceutics","tag-rejuvenation"],"acf":[],"yoast_head":"\nLongevity Science: The 4 Molecules of Longevity - SoLongevity<\/title>\n<meta name=\"description\" content=\"Resveratrol, polydatin, glutathione, and NAD+ are four of the so-called \u201clongevity molecules\u201d on which research has long focused.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Longevity Science: The 4 Molecules of Longevity - SoLongevity\" \/>\n<meta property=\"og:description\" content=\"Resveratrol, polydatin, glutathione, and NAD+ are four of the so-called \u201clongevity molecules\u201d on which research has long focused.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\" \/>\n<meta property=\"og:site_name\" content=\"SoLongevity\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/longevita.scienza.salute.solongevity\/\" \/>\n<meta property=\"article:published_time\" content=\"2022-08-30T14:01:10+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-19T17:20:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/solongevity.com\/wp-content\/uploads\/2022\/11\/shutterstock_1922147327-scaled12100257.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"valentinarachiele\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"valentinarachiele\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\"},\"author\":{\"name\":\"valentinarachiele\",\"@id\":\"https:\/\/solongevity.com\/en\/#\/schema\/person\/5c1f5b6d2b161ea2370ce61034e9b1d4\"},\"headline\":\"The 4 Molecules of Longevity\",\"datePublished\":\"2022-08-30T14:01:10+00:00\",\"dateModified\":\"2023-08-19T17:20:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\"},\"wordCount\":438,\"publisher\":{\"@id\":\"https:\/\/solongevity.com\/en\/#organization\"},\"image\":{\"@id\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/solongevity.com\/wp-content\/uploads\/2022\/11\/shutterstock_1922147327-scaled12100257.jpg\",\"keywords\":[\"Nutraceutics\",\"Rejuvenation\"],\"articleSection\":[\"News\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\",\"url\":\"https:\/\/solongevity.com\/en\/longevity-news\/the-4-molecules-of-longevity\/\",\"name\":\"Longevity Science: The 4 Molecules of Longevity - 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