{"id":14855,"date":"2022-08-23T16:05:43","date_gmt":"2022-08-23T16:05:43","guid":{"rendered":"https:\/\/solongevitypro.com\/?p=14855"},"modified":"2022-12-14T08:44:16","modified_gmt":"2022-12-14T08:44:16","slug":"resveratrol-a-potential-help-even-against-covid","status":"publish","type":"post","link":"https:\/\/solongevity.com\/en\/longevity-news\/resveratrol-a-potential-help-even-against-covid\/","title":{"rendered":"Resveratrol, a Potential Help Even Against Covid"},"content":{"rendered":"<h3 class=\"article-title\">A possible \u201cantiviral\u201d action<\/h3>\n<p>To combat\u00a0<strong>coronavirus<\/strong>, possible help could come from\u00a0<strong>resveratrol<\/strong>, a natural substance that has been shown to have dual action: antiviral, because it can prevent virus replication, and\u00a0<strong>anti-inflammatory<\/strong>, which could help counteract the more severe effects of Covid if used topically, directly on nasal mucous membranes. This was suggested by a group of Italian experts in the pages of\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8289612\/\">Frontiers of Immunology<\/a>, presenting the (still preliminary) results of some experiments in which resveratrol was shown to significantly\u00a0<strong>decrease<\/strong>\u00a0the\u00a0<strong>replication<\/strong>\u00a0of<strong>\u00a0Sars-Cov-2<\/strong>\u00a0(the virus that causes Covid-19) in nasal epithelium cells. As a\u00a0<strong>supplement<\/strong>, on the other hand, resveratrol has been used for years for its\u00a0<strong>antioxidant and anti-inflammatory<\/strong>\u00a0properties, which counteract the onset of<strong>\u00a0chronic diseases<\/strong>\u00a0and exert an\u00a0<strong>anti-aging<\/strong>\u00a0effect on our bodies. Given the many promises of this wonder of the plant world, here is a brief history of resveratrol and its properties.<\/p>\n<h3 class=\"article-title\">Resveratrol: what are we talking about?<\/h3>\n<div id=\"attachment_13957\" style=\"width: 1010px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" fetchpriority=\"high\" decoding=\"async\" aria-describedby=\"caption-attachment-13957\" class=\"wp-image-13957 size-full\" src=\"https:\/\/solongevity.com\/wp-content\/uploads\/2022\/11\/shutterstock_1178996821.jpg\" alt=\"grapes, raspberries, mulberries\" width=\"1000\" height=\"667\" \/><p id=\"caption-attachment-13957\" class=\"wp-caption-text\">Resveratrol is a natural molecule found in many types of fruits, including grapes, raspberries, mulberries<\/p><\/div>\n<p>Chemically speaking, it is a\u00a0<strong>non-flavonoid phenol<\/strong>, that is, an organic compound produced naturally by various plant species. For\u00a0<strong>plants<\/strong>, resveratrol is basically an\u00a0<strong>antiparasitic<\/strong>, helping them to defend themselves from attack by bacteria, fungi and other pathogens. Lucky for humans, because this means that resveratrol is present in\u00a0<strong>high amounts<\/strong>\u00a0in many fruits, such as\u00a0<strong>grapes<\/strong>,\u00a0<strong>raspberries<\/strong>,\u00a0<strong>mulberries<\/strong>,\u00a0<strong>blueberries<\/strong>, but also in\u00a0<strong>peanuts<\/strong>. To take full advantage of its\u00a0<strong>anti-inflammatory<\/strong>\u00a0and\u00a0<strong>anti-aging<\/strong>\u00a0properties, it is also possible to use dietary\u00a0<strong>supplements<\/strong>, remembering, however, that they are not all the same. The effects, in fact, change considerably depending on\u00a0<strong>dosage<\/strong>\u00a0and\u00a0<strong>combination<\/strong>\u00a0with other ingredients, which can enhance, or depotentiate, the effects of resveratrol.<\/p>\n<blockquote><p>Resveratrol is a polyphenol with anti-inflammatory and antioxidant properties, and also appears to be able to decrease the replication of the coronavirus responsible for Covid-19<\/p><\/blockquote>\n<h3>What are the limits?<\/h3>\n<p>Despite its many properties, resveratrol also has some \u201cweaknesses.\u201d For example, it is referred to as having \u201c<strong>poor bioavailability<\/strong>,\u201d because it does not readily pass the cell barrier in its pure form, and cells therefore have difficulty using it even when it is present within the body. This applies to its \u201cfinal\u201d form, but it is possible\u00a0<strong>to get around this problem<\/strong>\u00a0by using a\u00a0<strong>precursor<\/strong>, that is, a molecule that our body can use to produce resveratrol. This is the case with\u00a0<strong>polydatin<\/strong>, a glycosylated form of resveratrol that can easily cross the cell barrier and release its beneficial potential. Polydatin has also been shown to have an even greater ability than resveratrol to\u00a0<strong>counteract<\/strong>\u00a0the effects of\u00a0<strong>free radicals<\/strong>, and to activate some of the molecular pathways on which resveratrol acts.<\/p>\n<h3 class=\"article-title\">What are the mechanisms of action?<\/h3>\n<p>Looking at its beneficial properties, resveratrol is a powerful\u00a0<strong>antioxidant<\/strong>\u00a0that can\u00a0<strong>protect<\/strong>\u00a0cells from the negative effects of\u00a0<strong>oxidative stress<\/strong>, one of the main factors behind\u00a0<strong>aging<\/strong>. It is also able to\u00a0<strong>counteract inflammation<\/strong>, a mechanism that contributes to the onset of\u00a0<strong>chronic diseases<\/strong>\u00a0in the course of aging through so-called<strong>\u00a0inflammaging<\/strong>, that is, a low level of chronic inflammation that over time damages tissues, accelerating aging and worsening the effects of age-related diseases.<\/p>\n<blockquote><p>Resveratrol is used as a dietary supplement to counter the onset of chronic diseases and for an anti-aging effect on our body<\/p><\/blockquote>\n<p>More and more research also shows that resveratrol can improve the functioning of\u00a0<strong>mitochondria<\/strong>, the cell organelles where ATP (the fuel used by cells) is produced. This effect stems mainly from resveratrol\u2019s ability to modulate the activation of\u00a0<strong>sirtuins<\/strong>, proteins essential for the functioning of mitochondria, and in this way the substance is believed to be able to increase the activity of these cellular organelles, counteracting the onset of disorders such as\u00a0<strong>diabetes<\/strong>\u00a0and\u00a0<strong>obesity<\/strong>, and thus contributing to better health in old age.<\/p>\n<div id=\"attachment_14125\" style=\"width: 1010px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" aria-describedby=\"caption-attachment-14125\" class=\"wp-image-14125 size-full\" src=\"https:\/\/solongevity.com\/wp-content\/uploads\/2022\/11\/shutterstock_16502553251.jpg\" alt=\"\" width=\"1000\" height=\"667\" \/><p id=\"caption-attachment-14125\" class=\"wp-caption-text\">Resveratrol appears to regulate cell death, improving memory and cognitive abilities<\/p><\/div>\n<p>Finally, resveratrol appears capable of\u00a0<strong>regulating apoptosis<\/strong>, which is the process of programmed cell death. This is a fundamental mechanism for eliminating old or damaged cells, but it can be harmful when activated in healthy cells, as can occur in neurodegenerative diseases or other disorders. Thus, by decreasing apoptosis in neural cells, resveratrol is believed to\u00a0<strong>promote<\/strong>\u00a0<strong>memory<\/strong>\u00a0and\u00a0<strong>cognitive performance<\/strong>\u00a0in the elderly.<\/p>\n<p>Along with glutathione, NAD+ and polydatin, resveratrol is one of the so-called \u201clongevity molecules\u201d that\u00a0<a href=\"https:\/\/solongevity.com\/en\/nutraceutica\/\">SoLongevity research<\/a>\u00a0focuses on. On this site you can find an in-depth study dedicated to each molecule.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antioxidant and anti-inflammatory, resveratrol also appears to have antiviral action, limiting Sars-Cov-2 replication in nasal epithelium cells.<\/p>\n","protected":false},"author":1,"featured_media":462,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[158],"tags":[160,168],"class_list":["post-14855","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","tag-active-ageing","tag-nutraceutics"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Resveratrol, a Potential Help Even Against Covid - SoLongevity<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/solongevity.com\/en\/longevity-news\/resveratrol-a-potential-help-even-against-covid\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Resveratrol, a Potential Help Even Against Covid - 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