{"id":40787,"date":"2024-07-17T14:58:35","date_gmt":"2024-07-17T14:58:35","guid":{"rendered":"https:\/\/solongevity.com\/longevity-news\/intermittent-fasting-improves-gut-health\/"},"modified":"2026-10-19T08:12:42","modified_gmt":"2026-10-19T08:12:42","slug":"intermittent-fasting-gut-health","status":"publish","type":"post","link":"https:\/\/solongevity.com\/en\/longevity-news\/intermittent-fasting-gut-health\/","title":{"rendered":"Intermittent Fasting Improves Gut Health"},"content":{"rendered":"<p>It improves <strong>gut health<\/strong> and helps us manage our weight. It is <strong>intermittent fasting<\/strong>, a dietary pattern that alternates periods of fasting with periods of eating and that has gained popularity for its potential health <strong>benefits<\/strong>. Supporting evidence also comes from a recent <a href=\"https:\/\/www.nature.com\/articles\/s41467-024-48355-5\" target=\"_blank\" rel=\"noopener\">study<\/a>, published in <em>Nature Communications<\/em> and coordinated by Arizona State University, whose results help improve our understanding of the complex <strong>relationship between the gut microbiota and metabolism<\/strong> and pave the way for the development of potential <strong>dietary interventions<\/strong> effective against <strong>obesity<\/strong> and<strong> metabolic diseases<\/strong>.  <\/p>\n<h2>The role of the gut microbiota<\/h2>\n<p>The gut <strong>microbiota<\/strong> is the community of microorganisms that inhabit the intestine, namely bacteria, viruses, fungi and more. This complex ecosystem plays a crucial role both in essential bodily functions and in overall health. Among its various tasks, in fact, it helps break down food, produce vitamins and promote the absorption of nutrients. It also plays a role in the development and functioning of the<strong> immune system<\/strong> and regulates <strong>metabolism<\/strong>, influencing body weight, <strong>fat accumulation<\/strong> and <strong>insulin sensitivity<\/strong>.   <\/p>\n<div class=\"container-product-box\"><div class=\"product-box\"> <div class=\"badge\">SOLONGEVITY SHOP<\/div>    <div class=\"product-image\">        <img decoding=\"async\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0765\/8015\/9763\/files\/aminoage-hp-01.jpg?v=1718352615\" alt=\"AminoAge Plus. Nutraceutico di Nuova Generazione\">    <\/div>    <div class=\"product-details\">        <div class=\"product-title\">AminoAge Plus. Nutraceutico di Nuova Generazione        <\/div>        <div class=\"product-description\">L\u2019integrazione con <strong>aminoacidi essenziali<\/strong> pu\u00f2 aiutare a mantenere elevata la concentrazione di<strong> batteri 'buoni'<\/strong>, che tendono a diminuire con l\u2019et\u00e0, e a ridurre l\u2019inflammaging intestinale. Inoltre promuove la <strong>sintesi proteica<\/strong>, contrastando la perdita di <strong>massa muscolare<\/strong> (sarcopenia) che si verifica sia con l'invecchiamento sia in altre condizioni, come in seguito a <strong>diete ipocaloriche<\/strong>.        <\/div>        <div class=\"price-and-button\">            <div class=\"product-button\">                <a class=\"button\" href=\"https:\/\/shop.solongevity.com\/products\/aminoage-plus?variant=49219730243859&#038;currency=EUR&#038;utm_medium=intermittent-fasting-gut-health&#038;utm_source=corporate&#038;utm_content=sag_organic&#038;utm_campaign=banner\">Scopri di pi\u00f9 <\/a>            <\/div>        <\/div>    <\/div><\/div><\/div>\n<h2>The link between diet and microbiota<\/h2>\n<p>Previous research has already shown how certain eating patterns, for example<strong> caloric restriction<\/strong> and <strong>intermittent fasting<\/strong>, can influence <strong>weight<\/strong> as well as<strong> the composition of the gut microbiota<\/strong>, although the effect has still not been fully clarified. \u201cA healthy gut microbiota is essential for overall health, particularly in the management of obesity and metabolic diseases,\u201d explained Karen Sweazea, one of the study&#8217;s authors. \u201cGut bacteria influence how we store fat, balance glucose levels and respond to the hormones that make us feel hungry or full. Alterations in the gut microbiota, therefore, can lead to increased <strong>inflammation<\/strong>, insulin resistance and weight gain, underscoring the fundamental role of gut health in the prevention and management of<strong> metabolic disorders<\/strong>.\u201d   <\/p>\n<h2>Low-calorie regimens compared<\/h2>\n<p>In the study, the researchers involved 41 people (27 women and 14 men) with overweight or obesity, divided into two groups on the basis of the proposed dietary intervention: one group followed a <strong>healthy, low-calorie diet<\/strong>, in the style of the Mediterranean diet based on US dietary recommendations, while the other followed the <strong>IF-P<\/strong> regimen, that is, the combination of <strong>intermittent fasting<\/strong> and <strong><em>protein pacing<\/em><\/strong>, which could be rendered as \u201c<strong>protein stimulation<\/strong>\u201d. In detail, this is a high-protein diet that involves controlling the intake of <strong>protein<\/strong> at regular intervals, while intermittent fasting limits food consumption to certain times on some days.  <\/p>\n<p>The researchers monitored the participants over a period of 8 weeks and compared the <strong>effects<\/strong> of the low-calorie dietary patterns in both groups. In particular, they focused on assessing <strong>gut microbial composition<\/strong>, <strong>inflammatory molecules<\/strong> called <strong>cytokines<\/strong>, <strong>SCFAs<\/strong> (metabolites derived from dietary fiber, important for regulating energy balance) and the <strong>metabolome<\/strong>. <\/p>\n<h2>The help of intermittent fasting and protein supplementation<\/h2>\n<p>The analyses showed that those who followed the <strong>intermittent fasting<\/strong> regimen experienced a significant <strong>reduction in gastrointestinal symptoms<\/strong> and an <strong>increase in beneficial gut bacteria<\/strong>, particularly of the <em>Christensenellaceae<\/em> family. These bacteria, according to the researchers, are associated with better fat oxidation and metabolic health. The group that followed the Mediterranean-style <strong>low-calorie diet<\/strong> nonetheless showed an increase in metabolites associated with metabolic pathways that promote <strong>longevity<\/strong>.  <\/p>\n<p>Although both groups received a similar average weekly energy intake, the <strong>intermittent fasting<\/strong> group recorded<strong> greater weight loss and fat reduction<\/strong>: the percentage of lean body mass increased, while initial body weight decreased by an average of 8.81%. By comparison, those in the Mediterranean-style low-calorie diet group lost an average of 5.4% of their body weight. In addition, with intermittent fasting, levels of cytokines associated with<strong> weight loss<\/strong> increased, as did by-products of <strong>amino acids<\/strong> that promote <strong>fat burning<\/strong>.  <\/p>\n<p>Although further research is needed, these results underscore the potential of intermittent fasting and high-protein diets to improve gut health and weight management. \u201cThis line of work holds promise for <strong>creating personalized health strategies<\/strong> because, by identifying the specific changes in bacteria, functional pathways and associated metabolites, we can better tailor nutritional regimens to improve gut function and metabolic outcomes,\u201d concluded Alex Mohr, first author of the paper. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Different dietary regimens have different effects on the gut microbiota: identifying the changes could make it possible to develop personalized dietary strategies to combat obesity and other metabolic diseases <\/p>\n","protected":false},"author":10,"featured_media":28068,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[158],"tags":[355,341,167,356],"class_list":["post-40787","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","tag-intermittent-fasting","tag-metabolism","tag-microbiota-en","tag-obesity"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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