{"id":40817,"date":"2024-03-07T09:26:31","date_gmt":"2024-03-07T09:26:31","guid":{"rendered":"https:\/\/solongevity.com\/longevity-news\/cardioage-a-health-ally-for-blood-vessels\/"},"modified":"2026-10-19T09:57:33","modified_gmt":"2026-10-19T09:57:33","slug":"cardioage-blood-vessels","status":"publish","type":"post","link":"https:\/\/solongevity.com\/en\/longevity-news\/cardioage-blood-vessels\/","title":{"rendered":"CardioAge, a Health Ally for Blood Vessels"},"content":{"rendered":"

Over the years, blood vessels<\/strong> tend to deteriorate and lose<\/strong> their elasticity<\/strong>, and the number of capillaries<\/strong> also tends to decrease. This causes a reduction in the supply of blood<\/strong>, and therefore of oxygen, to organs and tissues, with consequences for the whole body. Fortunately, this is a situation we can help prevent<\/strong>, first and foremost<\/em> through a healthy lifestyle<\/strong>, and then with the help of supplements<\/strong> that counteract the age-related reduction in peripheral vascularization. <\/p>\n

Studies on NAD<\/h3>\n

The consequences of a reduced blood supply can be extremely varied, from cognitive decline<\/strong> to reduced muscle<\/strong> function. Muscles are particularly affected by poor vascularization, which incidentally creates a vicious circle: physical exercise in itself has a beneficial effect on the health of blood vessels, but a limited blood flow to the muscles causes a decrease in muscle mass and, therefore, a reduced ability to exercise. <\/p>\n

As explained in a video<\/a> published on social media by David Sinclair<\/strong>, professor at the Harvard Medical School (United States) center for research on the biology of aging, a solution to this vicious circle could be supplementation with NAD precursors<\/strong>: NAD levels tend to decrease with age, and through a cascade of events it promotes vascular regeneration in muscles. NAD<\/a> (nicotinamide adenine dinucleotide) is present in all cells and plays a central role in the metabolic processes that lead to energy production. <\/p>\n

According to a study<\/a> conducted in mice, published in 2018 in Cell<\/em> by Sinclair’s own research group, restoring NAD levels through its precursors promotes the activity of sirtuins<\/strong><\/a>, a class of proteins found in our body that perform countless functions. Increasing NAD levels means in particular promoting the activity of a specific sirtuin, SIRT1<\/strong>, which in turn promotes an increase in the number of capillaries<\/strong> in muscle fibers, thus helping to reverse the process of vascular<\/strong> aging. The results of the study in fact show that treatment with NAD precursors improves physical endurance by up to 80% in old mice. <\/p>\n

CardioAge<\/h3>\n

CardioAge<\/a>, the supplement produced by SoLongevity, contains niacin (or vitamin B3), a NAD precursor<\/strong>. For this reason it is suitable for promoting the health of blood vessels and of the cardiovascular system in general. In addition, CardioAge helps counteract the formation of atherosclerotic plaques in blood vessels by reducing homocysteine levels<\/strong>, an amino acid whose high concentration in the blood (hyperhomocysteinemia) is a cardiovascular and neurovascular risk factor. <\/p>\n","protected":false},"excerpt":{"rendered":"

Thanks to its formula, it helps counteract the age-related reduction in peripheral vascularization and the hardening of the vessels<\/p>\n","protected":false},"author":14,"featured_media":25900,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[158],"tags":[165,168,170],"class_list":["post-40817","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","tag-exercise","tag-nutraceutics","tag-prevention"],"acf":[],"yoast_head":"\nCardioAge, a Health Ally for Blood Vessels - SoLongevity<\/title>\n<meta name=\"description\" content=\"The number of small blood vessels tends to decrease with age, with consequences for the whole body and in particular for the muscles\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/solongevity.com\/en\/longevity-news\/cardioage-blood-vessels\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CardioAge, a Health Ally for Blood Vessels - 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