{"id":40817,"date":"2024-03-07T09:26:31","date_gmt":"2024-03-07T09:26:31","guid":{"rendered":"https:\/\/solongevity.com\/longevity-news\/cardioage-a-health-ally-for-blood-vessels\/"},"modified":"2026-11-03T16:09:28","modified_gmt":"2026-11-03T16:09:28","slug":"cardioage-blood-vessels","status":"publish","type":"post","link":"https:\/\/solongevity.com\/en\/longevity-news\/cardioage-blood-vessels\/","title":{"rendered":"CardioAge, a Health Ally for Blood Vessels"},"content":{"rendered":"

Over the years, blood vessels<\/strong> tend to deteriorate and lose<\/strong> their elasticity<\/strong>, and the number of capillaries<\/strong> also tends to decrease. This causes a reduction in the supply of blood<\/strong>, and therefore of oxygen, to organs and tissues, with consequences for the whole body. Fortunately, this is a situation we can help prevent<\/strong>, first and foremost<\/em> through a healthy lifestyle<\/strong>, and then with the help of supplements<\/strong> that counteract the age-related reduction in peripheral vascularization.<\/p>\n

Studies on NAD<\/h3>\n

The consequences of a reduced blood supply can be extremely varied, from cognitive decline<\/strong> to reduced muscle<\/strong> function. Muscles are particularly affected by poor vascularization, which incidentally creates a vicious circle: physical exercise in itself has a beneficial effect on the health of blood vessels, but a limited blood flow to the muscles causes a decrease in muscle mass and, therefore, a reduced ability to exercise.<\/p>\n

As explained in a video published on social media by David Sinclair<\/strong>, professor at the Harvard Medical School (United States) center for research on the biology of aging, a solution to this vicious circle could be supplementation with NAD precursors<\/strong>: NAD levels tend to decrease with age, and through a cascade of events it promotes vascular regeneration in muscles. NAD<\/a> (nicotinamide adenine dinucleotide) is present in all cells and plays a central role in the metabolic processes that lead to energy production.<\/p>\n

According to a study<\/a> conducted in mice, published in 2018 in Cell<\/em> by Sinclair’s own research group, restoring NAD levels through its precursors promotes the activity of sirtuins<\/strong><\/a>, a class of proteins found in our body that perform countless functions. Increasing NAD levels means in particular promoting the activity of a specific sirtuin, SIRT1<\/strong>, which in turn promotes an increase in the number of capillaries<\/strong> in muscle fibers, thus helping to reverse the process of vascular<\/strong> aging. The results of the study in fact show that treatment with NAD precursors improves physical endurance by up to 80% in old mice.<\/p>\n","protected":false},"excerpt":{"rendered":"

Thanks to its formula, it helps counteract the age-related reduction in peripheral vascularization and the hardening of the vessels<\/p>\n","protected":false},"author":14,"featured_media":25900,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[158],"tags":[165,168,170],"class_list":["post-40817","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","tag-exercise","tag-nutraceutics","tag-prevention"],"acf":[],"yoast_head":"\nCardioAge, a Health Ally for Blood Vessels - SoLongevity<\/title>\n<meta name=\"description\" content=\"The number of small blood vessels tends to decrease with age, with consequences for the whole body and in particular for the muscles\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/solongevity.com\/en\/longevity-news\/cardioage-blood-vessels\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CardioAge, a Health Ally for Blood Vessels - 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