CardioAge, a Next-Generation Supplement for Cardio and Neurovascular Wellness

Article by SoLongevity Research
SoLongevity Nutraceuticals is launching a new product, developed to regularize homocysteine and glutathione levels, promote blood vessel health, support cell energy metabolism, and contribute to cardio and neurovascular wellness

What this article is about

  • After three years of research and development and a publication in the prestigious journal Nutrients, SoLongevity Nutraceuticals has developed a supplement that can provide metabolic support for vascular wellness.
  • CardioAge works on multiple levels, converting a possible problem into a source of wellness for the body. In particular, it helps to regularize excess homocysteine levels by converting it into two components central to our health: glutathione and methyls. The former is among the most powerful antioxidants in our bodies; the latter are essential co-factors for the activity of amino acids and enzymes central to neurological, cardiovascular, and energy processes.
  • CardioAge is recommended for those with cardiovascular risk conditions and neurocognitive disorders.

CardioAge, SoLongevity’s new nutraceutical

From SoLongevity research comes CardioAge, a next-generation supplement developed to provide metabolic support for circulatory health, particularly suitable for those with risk factors for heart attack and stroke, and generally for all cardio- and neurovascular diseases.

CardioAge. Cardio and neurovascular wellness

What is homocysteine?

We all know the classic factors that put the heart and blood vessels at risk, such as having hyperglycemia or diabetes, high blood pressure, hypercholesterolemia, being overweight and obese, having a family history of these conditions, or having had previous heart attacks and strokes. And we also know about unhealthy lifestyles, such as sedentary lifestyle and smoking habits. Less well known is another risk factor: the presence of high levels of homocysteine (hyperhomocysteinemia), an amino acid, in the blood.

“Hyperhomocysteinemia is a little-known cardio- and neurovascular risk factor. It is detected by a simple blood test and can help the physician get a better picture of the individual’s risk for stroke, heart attack, and vascular disease.”

Hyperhomocysteinemia has a negative effect on the health of the vascular system because it promotes the processes of atherosclerosis: it alters both directly and indirectly the structure of the vessels and the functions of the endothelium lining them. The Are various causes of hyperhomocysteinemia: enzyme defects, diseases (hypothyroidism, renal failure, tumors, and a rare disease called homocystinuria), nutritional deficiencies, and side effects of drugs. In addition, 10 to 15 percent of the Italian population (about 20 percent in the South), have variants in the gene coding for 5-mtfh reductase that can promote this condition.

To measure homocysteine levels, a simple blood test, which can be prescribed by your doctor, is sufficient to get a more complete picture of your cardio and neurovascular risk

How does CardioAge work?

Based on the evidence, after three years of research and development and the publication of a study in the prestigious scientific journal NutrientsSoLongevity has developed CardioAge, which helps regularize homocysteine levels by converting it into endogenous glutathione , one of the most powerful antioxidants in our bodies, and into a source of methyls.. But that’s not all: CardioAge helps prevent or delay the onset of aging-related conditions and helps regularize the biochemical processes that lead to the synthesis of many substances useful for cell physiology and, consequently, for overall health. Its formulation is designed to ensure high bioavailability.

“CardioAge contributes to the control of homocysteine levels, protecting blood vessels. It also contributes to normal cell energy metabolism, helping to reduce fatigue and tiredness by providing riboflavin (Vit. B2) and niacin (Vit. B3). Finally, it promotes the endogenous production of glutathione, also providing vitamin B6 and folate, both directly and indirectly.”

Who is CardioAge suitable for?

CardioAge is indicated for all people with cardio- and neurovascular risk factors, especially those with elevated homocysteine levels. It is also recommended for individuals who are folate deficient, that is, who have insufficient levels of methylation, due to chronic conditions (such as hypothyroidism) or due to the consumption of medications (e.g., contraceptives) or due to a diet where the “green” component is absent or very low. It can also be used to support the maintenance of good cardiovascular and metabolic health above age 45, particularly if one has a “pro-oxidant” lifestyle, in menopausal women (when cardiovascular risk increases due to hormonal changes), and in those with age-related neurocognitive disorders.

CardioAge. Cardio and neurovascular wellness

“CardioAge regulates homocysteine, is an antioxidant booster and a source of methyls.”


Vezzoli, A.; Dellanoce, C.; Maria Caimi, T.; Vietti, D.; Montorsi, M.; Mrakic-Sposta, S.; Accinni, R. Influence of Dietary Supplementation for Hyperhomocysteinemia Treatments. Nutrients 202012, 1957. https://doi.org/10.3390/nu12071957

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