Flavia Franconi has lived several lives. A graduate in Psychiatry, she taught Pharmacology at the University of Sassari. She then served as Health Councillor of Basilicata. But women’s health has always been at the center of her interests. Indeed, she is the “noble mother” of sex-gender medicine in Italy, and today she is also at the center of an international network as chair of the Women20 Health Commission. We asked her to tell us about the differences between the sexes when it comes to aging.
Inflammaging, or chronic low-grade inflammation, is defined as a state of low-grade inflammation that can promote the onset of chronic diseases related to aging
Changes to the sleep-wake cycle can alter hormonal control over appetite and satiety, contributing to weight gain and increasing the risk of metabolic syndrome and diabetes
Five minutes of immersion in water at 20°C can cause a marked improvement in mood, and underlying these effects appear to be changes in functional connections between different brain areas
An advanced check-up of physical health status and cognitive performance, and risk factors for aging-related diseases. With an individualized program aimed at slowing biological age
Rapamycin, currently used as a post-transplant anti-rejection drug, appears to counteract the age-related reduction in histone expression. However, it can cause even serious side effects
A consensus document from the European Atherosclerosis Society gives physicians new guidance for testing and treating high blood Lp(a) concentrations
In 2013, nine causes of aging had been explained. About ten years later, the number rises to 12
A genetic variant very common in centenarians appears to have the ability to restore the function of certain heart cells, improving overall organ function and turning back the hands of the biological clock
Excess homocysteine poses a health risk to the cardio- and cerebrovascular system because it stimulates the development of atherosclerosis, increasing the likelihood of stroke and heart attack. If action is taken early, by changing dietary habits and through supplements, levels can be normalized. With a double advantage
Focusing only on treating chronic diseases when they occur is not a sustainable strategy. A change of perspective is needed: to invest, first, in healthy longevity. This is the philosophy of SoLongevity and other major players in Geroscience, who sign a manifesto of intent in Lancet Healthy Longevity
Many metabolic processes in the body produce free radicals that, under balanced conditions, are neutralized by antioxidants. Some external agents, however, as well as certain habits and diseases, increase the production of free radicals excessively, and generate a state of oxidative stress that is dangerous to health
SoLongevity Nutraceuticals is launching a new product, developed to regularize homocysteine and glutathione levels, promote blood vessel health, support cell energy metabolism, and contribute to cardio and neurovascular wellness
Certain epigenetic mechanisms underlie the aging processes in many mammalian species, including humans. This is the basis of the watch of Steve Horvath, a pioneer in biological age research
An American study measured the effects of urolithin A supplementation on muscle endurance and mitochondrial health. The results suggest that the substance aids a process called mitophagy, by which cells replace damaged mitochondria
A new mathematical model recalculates the theoretical maximum human lifespan, bringing it up to 150 years
There are many studies that are trying to define the optimal eating style to increase the number of years lived healthy. Much of the research focuses on intermittent fasting to determine what the best time window is. Exploring this world is a review by Italian scientist Valter Longo in Cell.
Once seen only as helpful and protective, we now know that inflammation can contribute to the development of numerous diseases
When it comes to cardiovascular disease, the age of our immune system matters more than age. Today, the iAge “inflammatory clock” allows us to estimate it. How does it work?
SoLongevity is the only Italian company to join the National Innovation Center for Aging (N.I.C.A.) in the UK, one of the most advanced international realities in the world in basic and translational research on aging. Mission: to transform longevity medicine and technology into services for the general public.
115 years is the estimated intrinsic capacity of the human being to live. But how long we live, and how we live, does not depend solely on our genes. Epigenetic studies have shown that there are mechanisms that can repair DNA damage and increase longevity.