Intimate life in menopause changes, but vaginal atrophy, pain and low desire have solutions. From topical therapies to vaginal laser and regenerative medicine, Dr. Raffaela Di Pace sheds light on the possible treatments for regaining balance and pleasure.
Between false myths about the risks of hormone replacement therapy and new non-hormonal solutions, Dr. Raffaela Di Pace guides us beyond the silence surrounding intimate disorders and the symptoms of menopause, reminding us that living this transition in full health and harmony is a right and a possible choice.
Between conferences, debates and well-being “raves” at Allianz MiCo, Milan explores the new frontiers of longevity medicine. A journey in four stages that will culminate in Rome to bring together science, ethics and social responsibility.
We discuss it with Maria Letizia Scaglioni, nutritionist biologist at the SoLongevity Clinic in Milan
How is gut health connected to longevity? Interview with Francesca Jaboli, gastroenterologist at the SoLongevity Clinic in Milan
A study conducted on pairs of twins raises the role of genetics in determining lifespan: from less than 25% to over 50%. The comment of Alberto Beretta, President and Scientific Director of SoLongevity
A review of studies on the microbiota-gut-brain axis reveals how two-way communication between the digestive system and the central nervous system regulates sleep-wake cycles. Interview with Ginevra Pignata, neuroscientist and part of the medical team of the SoLongevity Clinic in Milan, who stresses the importance of a holistic approach
Between promises of eternal youth and the trends of the moment, longevity medicine is experiencing an unprecedented boom. But to avoid unnecessary risks, the supervision of expert clinicians within a medical context is always needed
It is a help at all ages that makes it possible to address various types of problems, not only those that often arise after childbirth or in menopause. Interview with Sabina Pelizzari, physical therapist specializing in abdominal-pelvic rehabilitation
Through a thorough checkup and personalized interventions dedicated to the FemGevity pathway, the program aims to prevent problems linked to this period of a woman’s life and to preserve long-term quality of life. As explained by Alberto Cerasari, Medical Director and clinical lead of SoLongevity
Longevity medicine involves an integrated approach to health, which also includes the urological and andrological consultation to ensure a high quality of life at any age
Although it has been shown that lifestyles play a leading role in combating disease and maintaining health, also from a longevity perspective, their integration into the healthcare system is a rare event. In this article we analyze the 6 lifestyle pillars of longevity and why it is important that they be prescribed by physicians as if they were drugs
The first checkup between ages 16 and 20 not only makes it possible to ascertain the health of the urogenital system, but is also a moment of education and prevention to remain healthy and “high-performing” for a long time
Even today men's health is surrounded by taboos and little willingness to face and solve problems, especially when it comes to sexuality and the urogenital system. Men often turn to friends, the internet or their partner before seeking a doctor's opinion. However, for...
Metabolic syndrome refers to the simultaneous presence of several factors that pose a risk for the onset of cardiovascular disease
Menopause can have a very negative impact on careers and leads two women out of five to look for a new job. This is shown by a study by the Society for Women’s Health Research, which has created a road map to guide companies in adopting supportive policies
Drug therapies, but not only: to prevent and manage osteoporosis, a plan that includes personalized nutrition and physical activity pathways is essential
Precision Longevity™ is the philosophy that permeates all the activities of SoLongevity and the SoLongevity Clinic: combining the principles of precision medicine with those of longevity science for a tailor-made longevity project
SoLongevity offers a multidisciplinary program that starts from monitoring sleep and daily activities to develop a plan to improve the quality of rest. Here is how it works
From molecular hydrogen treatment to intravenous therapies, from cycles of hypoxia and hyperoxia to ozone therapy, from photobiomodulation to breath therapy. Let’s find out which accelerators of physiological rejuvenation are used at the SoLongevity Clinic, and how they work
Partly because of fluctuations in estrogen levels, menopause often brings with it a series of changes that concern not only the reproductive system, but also the central nervous system
Infusion therapies can have two main objectives: supplementation or enhancement. At the SoLongevity Clinic, each treatment is chosen and calibrated for the individual person after a careful clinical assessment, as explained by Roberta Costanzo, physician expert in Regenerative and Enhancement Medicine
The mechanisms that make cells age number more than 10, but since they are all interconnected, correcting one or two of them is enough for the system to return to balance” points out Dr. Alberto Beretta, immunologist, researcher and Filorga ambassador Go to the...
On the occasion of the Milan Longevity Summit, from March 27 to 29, it will be possible to take part in workshops with the leading longevity experts. See you at the Teatro Franco Parenti in Milan
Discover how dynamically performed blood glucose measurement can help personalize nutrition and improve metabolic health
As we saw in the article “How About You, Can You Breathe Well?”, breathing is fundamental to life and regulates several physiological processes. Doing it efficiently, however, can change life and even lengthen it.
How does sleep change with age? How does it affect the main physiological systems? Here is why resting well helps you feel better and how to improve sleep quality
Within the major event, the days of March 27-28-29 are entirely organized by the SoLongevity Foundation at the Teatro Franco Parenti. With internationally renowned scientists, talks, round tables and over 40 workshops. From biological clocks that measure our true age to practical advice on nutrition, sleep, sport, dermatology
Brain Boost Program combines precision diagnostics and personalized medicine to improve cognitive function. Through a module-structured pathway, it acts on memory, attention, and executive skills, considering metabolic, neurological, and lifestyle factors. A comprehensive method to preserve and enhance cognitive performance over time
SoLongevity launches Brain Boost Program, a comprehensive diagnostic and intervention program dedicated to boosting cognitive reserve and preserving cognitive health. From checkups to personalized cognitive training: to improve memory and increase concentration, fighting mental fatigue and counteracting brain aging
During autumn and winter, it is important to help the immune system maintain or regain its balance in order to fight more effectively the viruses responsible for colds, flu and Covid. Here is how
There is often confusion about these products and about what effect can be expected when taking them. Let’s clarify with the SoLongevity experts
Breathing can be trained through exercises to enhance health and longevity. Discover SoLongevity’s Breath Training Program
Loris Bonamassa is an entrepreneur from the Veneto region, founder of the family business. He was President of the Gruppo Sistemi per Dormire (Federlegno) and Representative in the European Bedding Industries Association (EBIA). He brought the figure of the Sleep Coach to Italy and founded the STB Sleep Trainer Bonamassa Academy, which trains and certifies “sleep trainers”, in collaboration with physicians, scientific societies and professional sport. He is a member of various associations, including: World Sleep Society (WSS), Italian Society of Dental Sleep Medicine (SIMSO), European Sleep Research Society (ESRS), Narcolepsy Network Organization, Perform SMC – Sport Medical Center, Med&Sport First Integrated Academy, International Sports Science Association (ISSA Europe), SANIS Kinetic Fitness & Performance School. He has written numerous popular books on sleep, including “L’arte del dormire” (“The Art of Sleeping”) and the latest, “Sonno e sorrisi” (“Sleep and Smiles”), published by Rubbettino (2023).
Born in 1975, with a degree in Political Science and a PhD in Women’s Issues and Equal Opportunity Policies, Eleonora Selvi works in the third sector and, in particular, on issues related to aging. She is President of the Longevitas Foundation and of the association Cuore Nostro, committed to promoting heart health.
It is the discipline that studies the products of the reactions that take place within an organism. Among its many applications is the one that makes it possible to identify nutritional needs in detail
At its clinic, SoLongevity offers the Age360 Checkup program, whose diagnostic goal is to promote significant physiological rejuvenation by fostering and stimulating the body's natural regulatory mechanisms. The more than 25 parameters collected in phases one and two...
The same expression is used to indicate different aspects: from circadian rhythms, such as the sleep-wake rhythm, to systems for measuring biological age. Let’s clarify
SoLongevity’s first clinic in Italy offers Precision Longevity™—a medical space designed to help you achieve healthy longevity goals and take a personalized approach to active prevention.
A 24-year study confirmed the inverse correlation between VO2 max and the risk of death from cardiovascular disease, cancer and other causes
Also known as nutraceutical products or nutraceutical supplements, they are a new generation of dietary supplements containing substances able to support the body’s physiological processes
At the congress of the Italian Society of Nutraceuticals (SINut), SoLongevity Nutraceuticals presented the first results of a new monitoring system that makes it possible to detect, from a drop of blood, a series of molecules involved in oxidative stress and in the energy metabolism of cells
SoLongevity launches Sport Longevity Hub: the most up-to-date scientific knowledge and expertise of Solongevity staff to check one’s starting health status and set up the most suitable training path for each person
One form of the protein, alpha-Klotho, exerts an antioxidant, anti-inflammatory and anti-aging effect on various organs. Is it possible to measure it? And is it possible to increase its synthesis in those who are genetically predisposed to deficiency?
Different dietary regimens have different effects on the gut microbiota: identifying the changes could make it possible to develop personalized dietary strategies to combat obesity and other metabolic diseases
Its discovery is the result of a study by the University of Padua. Its inhibition causes the onset of premature senescence
A large study conducted in the United Kingdom shows that individuals with a high genetic risk can extend their life expectancy by adopting a healthy lifestyle
The gut bacteria that influence body mass index, fat mass and waist circumference differ between males and females
BioClock SoLongevity is launched: the program that makes it possible to measure biological age and design a tailor-made program to turn back the hands of the biological clock while promoting the person’s health
If a centenarian says she drank a liter of wine every day of her life, does the rule apply that a liter of wine a day keeps the doctor away? Obviously not. It is called “survivorship bias”, as Bradley Elliott explains in The Conversation. Let us see what it is
They are called the “building blocks of life” because they make up all the proteins present in living organisms, which are indispensable for every biological function. Let us find out how many there are and which ones, how they are classified and how they are synthesized
Interview with Alessandro Orlandini, physician-formulator and Italy’s foremost recognized expert in the field of amino acid nutrition
Essential amino acids have many anti-aging properties. From SoLongevity research comes AminoAge Plus, a new nutraceutical designed to optimize them
Epigenetics is a field of biology that studies changes in DNA that modify gene expression but do not involve alterations in the sequence of the genetic code
Mitochondria are cellular organelles indispensable for producing the energy used for metabolic functions
The exposome is the set of environmental stimuli that come into contact with the body. Here is why it is important to study it
Diet, physical activity, sleep, no smoking, and control of weight, cholesterol, blood sugar and blood pressure. These are the fundamental points according to the American Heart Association. Let us look at them in detail
The term biohacking is used to indicate practices aimed at managing or modifying environmental factors and lifestyle in order to influence one’s own biology
It is actually the most perceptible form, determined by certain visible signs such as wrinkles, skin tone and radiance. It is determined by intrinsic aging, that is, the mechanisms underlying cellular senescence that damages the skin layers, causing loss of density...
According to Beretta, “The thin boundary between the epidermis and the dermis is the meeting point of skin and systemic longevity. This is where cocktails of active ingredients, cosmetic and systemic, come together to protect and support the physiological mechanisms...
As part of the program of meetings and round tables of the Milan Longevity Summit, Filorga is taking part in the March 25 day organized by the SoLongevity Foundation, entitled «Living Longevity, from the frontiers of Science to everyday life», which will explore the...
The date is March 25, when Filorga will take part in the event organized by the SoLongevity Foundation on the theme Living Longevity, from the frontiers of Science to everyday life. Go to the article
It is never too late: there is no age limit for starting to eat well. Health benefits can be seen at any age, even if you start making healthier food choices later in life.” explained Dr. Hellas Cena Go to the article
To live long and keep a youthful appearance, you need a global approach that includes sport, diet, stress-management techniques, cryotherapy or intermittent fasting to reduce inflammation and benefit the dermis.” explains Alberto Beretta Go to the article
The thin boundary between the epidermis and the dermis is the meeting point of skin and systemic longevity.” says Dr. Alberto Beretta, President and Scientific Director of SoLongevity and Filorga Opinion Leader Go to the article
As Alberto Beretta, immunologist, scientific director and founder of SoLongevity as well as Filorga Opinion Leader, explains: “Skin aging is a mirror of the aging of the body: the skin undergoes extrinsic aging – above all from the sun – and intrinsic aging, which...
Senolytics are molecules that interfere with the metabolism of senescent cells and specifically eliminate them
The famous 10,000 steps a day needed to stay active and healthy have no real scientific basis. Here is what the scientific community has discovered so far about the importance of walking and how much we should do it
Nicola Palmarini is one of the world’s leading experts in innovation in aging and longevity and is the director of the UK’s National Innovation Centre for Ageing (NICA)…
Telomeres are the end parts of chromosomes and protect DNA. Here is why they are important
A new study suggests the possibility that the syndrome is correlated with premature brain aging. Physical activity and lifestyle changes could therefore help reduce the risk
Thanks to its formula, it helps counteract the age-related reduction in peripheral vascularization and the hardening of the vessels
Emanuela Notari, Longevity Strategist and Developer of Corporate Demographic Intelligence, is an expert in longevity planning and economics, and in developing companies’ demographic intelligence. Co-founding partner of A.L.I. Active Longevity Institute, she was previously Editorial Director of a small financial publishing house and, before that, had a twenty-year career in communications and advertising, culminating in the roles of
General Manager and then CEO of the Italian and Mexican subsidiaries, respectively, of the American multinational Young & Rubicam.
A new study conducted by Roberta Gualtierotti of the Policlinico di Milano suggests that these cellular power plants may not work as they should in people affected by the disease
From March 14 to 27, 2024, Milan hosted the leading international longevity experts: here is the Summit program.
The combination of the two types of training has been shown to have positive effects on people with a mild form of cognitive decline
February 2 is Wear Red Day, the American Heart Association initiative to raise awareness among women around the world about the risk of cardiovascular disease. A risk that can, however, be reduced through prevention and research
Some immune cells are activated in the muscles during physical activity to reduce inflammation. This could be a more general mechanism through which exercise helps promote our health
Researchers at Stanford University have developed a method to calculate the biological age of 11 body districts. This metabolomic clock could predict the development of dysfunction even before symptoms occur
According to a study published in Advanced Science, patients with mild to moderate forms of Covid-19 tend to recover faster when treated, in conjunction with antiviral therapy, with a combination of precursors of this molecule
An all-Italian research team has engineered a protein that promotes the exchange of information between neurons, making it activatable through the administration of rapamycin
Regular physical activity is essential for staying healthy, but, according to the results of a study published in Cell Metabolism, overdoing it may even become counterproductive
What is age-related frailty? And how does it show up in the two sexes? And is it possible to prevent it? Francesca Baglio, a neurologist at the IRCCS Fondazione Don Carlo Gnocchi ONLUS in Milan and a member of the SoLongevity scientific committee, tells us.
As we age, some cells of the immune system seem to lose their memory and revert to resembling those of infants. This makes them less effective in responding to previously encountered pathogens and could have implications in the development of new vaccines
Sounds composed of more powerful low frequencies seem to promote deep sleep and better cardiac function
Flavia Franconi has lived several lives. A graduate in Psychiatry, she taught Pharmacology at the University of Sassari. She then served as Health Councillor of Basilicata. But women’s health has always been at the center of her interests. Indeed, she is the “noble mother” of sex-gender medicine in Italy, and today she is also at the center of an international network as chair of the Women20 Health Commission. We asked her to tell us about the differences between the sexes when it comes to aging.
Inflammaging, or chronic low-grade inflammation, is defined as a state of low-grade inflammation that can promote the onset of chronic diseases related to aging
Changes to the sleep-wake cycle can alter hormonal control over appetite and satiety, contributing to weight gain and increasing the risk of metabolic syndrome and diabetes
Five minutes of immersion in water at 20°C can cause a marked improvement in mood, and underlying these effects appear to be changes in functional connections between different brain areas
The microbiota is the collection of a great many microorganisms that inhabit our bodies, with which we maintain a relationship of mutual exchange: we provide them with the nutrients they need, while they perform physiological, metabolic and immunological functions important to our physical and mental well-being
The word metabolism, derived from a Greek word meaning “mutation,” denotes the set of chemical and biochemical transformation processes that food undergoes from the moment we ingest it
Sirtuins are proteins that occur naturally in our body and regulate some important metabolic processes, Overall, their action aims to reduce cell replication, consequently slowing down the aging process
Aging is a physiological process whereby the various functions of a certain organism tend to progressively deteriorate over time. Although you cannot stop the hands of the clock, there are several steps you can take to ensure that you age as healthily as possible. Let’s see which ones
Dogs that eat only once a day seem to retain their cognitive abilities longer and generally have better health status
To function well, the immune system, and particularly its cellular components, need to maintain a proper energy balance
The immune system protects us from attack by pathogens through two types of responses: innate and acquired immunity. The first is very quick and powerful, but not specific. The second, in contrast, is slower and is specific. The latter is based on the activation of highly specialized cells, B lymphocytes and T lymphocytes
Hellas Cena, Vice-Rector for the Third Mission at the University of Pavia, is a physician specializing in Food Science with a focus on Dietetics and Diet Therapy, a university professor and head of the Laboratory of Dietetics and Clinical Nutrition, as well as the nutrition lead for the Provita center in Pavia affiliated with the University, and Head of the Dietetics and Clinical Nutrition Unit, ICS Maugeri I.R.C.C.S., Pavia.
We call it “gender medicine,” but it would be more correct to call it “sex-gender medicine.” Its goal is to ensure increasingly adequate treatment for all and equity of access to care, through the recognition and enhancement of differences between male and female individuals
An increase in this amino acid in the blood, which may also be diet-dependent, increases the risk of several aging-related diseases
The reasons why women have a greater need for sleep than men lie in certain aspects of biology, but are also cultural and social
An advanced checkup of physical health status and cognitive performance, and risk factors for aging-related diseases. With an individualized program aimed at slowing biological age
Those taking higher doses of magnesium have, on average, a higher gray mass volume and fewer white matter lesions. However, further studies will be needed to confirm these results
Rapamycin, currently used as a post-transplant anti-rejection drug, appears to counteract the age-related reduction in histone expression. However, it can cause even serious side effects
A consensus document from the European Atherosclerosis Society gives physicians new guidance for testing and treating high blood Lp(a) concentrations
According to a study published in Scientific Reports, exercises involving breath control appear to have a positive impact on stress symptoms
Several studies support the hypothesis that the efficacy of immunotherapy can be prolonged over time by acting on mechanisms that regulate intracellular oxidative stress
In 2013, nine causes of aging had been explained. About ten years later, the number rises to 12
Fofo stands for “fear of finding out,” or fear of discovering that you suffer from a certain health problem. And the
consequence is a possible delay in treatment
Guendalina Graffigna, Full Professor of Consumer and Health Psychology and Director of the EngageMinds HUB Research Center – Consumer, Food, Health Engagement Research Center at the Università Cattolica del Sacro Cuore in Cremona
The immune system protects us from potential threats, but if it is not functioning at its best it can give rise to exaggerated processes of inflammation and oxidation, which damage the body and promote aging and related diseases. “Feeding” it correctly is imperative
Vascular problems and oxidative stress underlie the decline in cognitive performance associated with aging, and may contribute to the development of dementia and Alzheimer’s disease. But action can be taken to reduce risks
A genetic variant very common in centenarians appears to have the ability to restore the function of certain heart cells, improving overall organ function and turning back the hands of the biological clock
“Longevity proteins” are now the focus of numerous studies that are investigating their possible preventive role against neurodegenerative diseases
In the last twenty years medicine has undergone a great revolution. The acceleration in genomics and other omics sciences has led to a profound change in the approach to the prevention, diagnosis, and treatment of diseases
One in 4 Italians – and one in 2 among those over 50 – suffers from metabolic syndrome. Here’s how to diagnose it and how to intervene to reduce the risk of metabolic and vascular diseases
The idea that speeding up metabolism is helpful for losing weight fast is mostly a false myth. This is what the science shows us.
Excess homocysteine poses a health risk to the cardio- and cerebrovascular system because it stimulates the development of atherosclerosis, increasing the likelihood of stroke and heart attack. If action is taken early, by changing dietary habits and through supplements, levels can be normalized. With a double advantage
There are several methods for measuring oxidative stress. Knowing one’s “level” of oxidative stress can be useful in a preventive and healthy aging perspective
Telomere length is considered one of the hallmarks of aging, but new research is revealing that their “measurement” seems to be indicative more of health status than biological age. As Valentina Bollati, associate professor in the Department of Clinical and Community Sciences and the Epiget Lab at Milan State University, explains.
The biological age of an organism is a significant indicator of health status and susceptibility to illness. Individual organs and tissues may undergo different aging processes, but the real challenge is to define a biological clock that applies to the whole organism, and that translates into parameters that are easy to monitor and act upon.
Measuring chronic latent inflammation is not as simple as measuring acute inflammation associated with infection or disease. There are different types of tests and markers, with different sensitivities. Here is a brief guide to get your bearings
A study published in Cell suggests this. Researchers investigated the effects on the intestinal flora from sweeteners such as aspartame, saccharin, stevia or sucralose, and also analyzed their effects on blood glucose
Fermented foods are showing beneficial health properties. Here are a few, for every palate
Focusing only on treating chronic diseases when they occur is not a sustainable strategy. A change of perspective is needed: to invest, first, in healthy longevity. This is the philosophy of SoLongevity and other major players in Geroscience, who sign a manifesto of intent in Lancet Healthy Longevity
After menopause, women’s cardiovascular risk is quite comparable to that of men, yet it is underestimated even by health professionals
Many metabolic processes in the body produce free radicals that, under balanced conditions, are neutralized by antioxidants. Some external agents, however, as well as certain habits and diseases, increase the production of free radicals excessively, and generate a state of oxidative stress that is dangerous to health
SoLongevity Nutraceuticals is launching a new product, developed to regularize homocysteine and glutathione levels, promote blood vessel health, support cell energy metabolism, and contribute to cardio and neurovascular wellness
Roberto Pusinelli (40) and Violante Lama (42), competing with the Italian national team at the European Rowing Championships, participate in SoLongevity research to understand how to improve mitochondria efficiency and provide answers to combat Long Covid
Certain epigenetic mechanisms underlie the aging processes in many mammalian species, including humans. This is the basis of the watch of Steve Horvath, a pioneer in biological age research
Certain foods are associated with lower levels of inflammation, as measured by specific markers such as C Reactive Protein. Here are what these “shield” foods are for our health.
An American study measured the effects of urolithin A supplementation on muscle endurance and mitochondrial health. The results suggest that the substance aids a process called mitophagy, by which cells replace damaged mitochondria
A new mathematical model recalculates the theoretical maximum human lifespan, bringing it up to 150 years
There are many studies that are trying to define the optimal eating style to increase the number of years lived healthy. Much of the research focuses on intermittent fasting to determine what the best time window is. Exploring this world is a review by Italian scientist Valter Longo in Cell.
Resveratrol, polydatin, glutathione, and NAD+ are four of the so-called “longevity molecules” on which research has long focused. In a series of four articles we explain what they are and how they work.
SoLongevity research has developed a patented, clinically tested formula that can rebalance the Redox status and reduce inflammation, with the aim of preventing age-related decline in cognitive ability.
It is one of the most powerful natural antioxidants in our bodies. It plays a central role in tissue production and repair and defends us against numerous diseases. And it plays an important role in physiological processes related to aging.
Antioxidant and anti-inflammatory, resveratrol also appears to have antiviral action, limiting Sars-Cov-2 replication in nasal epithelium cells.
A diet rich in these foods increases the diversity of microorganisms in the gut microbiome and reduces inflammation.
NAD+ is a molecule involved in cellular metabolism and aging. As the age increases, its level actually decreases. But with appropriate supplementation, it can be restored.
Once seen only as helpful and protective, we now know that inflammation can contribute to the development of numerous diseases
Conducted by SoLongevity Research in collaboration with Sacco Hospital in Milan, the study will assess in more than 150 patients the efficacy of the nutraceutical on the redox state and on the symptoms of the disease, in particular on tiredness, brain fog and sleep quality.
High levels of antioxidants in the blood, in middle age and in older adults, are on average associated with a lower risk of later developing a form of dementia
PM2.5 particulate matter lowers the levels of a protein, sirtuin 2, which regulates important physiological processes underlying airway inflammation. This is revealed by a study that also identifies a potential therapeutic avenue
After GluRes, SoLongevity’s first patent, the GluReNAD nutraceutical formulation is also covered by a patent: by mimicking the effects of caloric restriction, it regulates metabolism and also helps reduce the sense of hunger thanks to the energy boost provided by the synergy of glutathione, resveratrol and NAD
One of the measures of biological age, telomere length, could predict the risk of developing severe forms of COVID-19. The finding applies above all to women over 65
The new coronavirus has been shown to have neurological and neuropsychiatric effects even in the long term. These mechanisms and the hypothesis that inflammation predisposes to the development of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, are being investigated.
According to a study conducted by IFOM in Milan and IGM-CNR in Pavia, the reason why older people are more susceptible to the SARS-CoV-2 virus could be linked to aging-related genetic damage
A polyphenol with antioxidant and anti-inflammatory properties, polydatin is a natural bioavailable molecule that also appears to reduce the infectivity of the coronavirus
A study conducted by SoLongevity Research and the University of Verona, published in eBioMedicine, reveals important new information on the serological response to vaccines. The presence of type M immunoglobulins is associated with a higher antibody level and a greater ability to neutralize the virus. And it suggests that the response to vaccination may depend on pre-existing immunity developed against other coronaviruses
Measuring one’s state of health against an ideal aging process allows us to understand how well we are able to preserve our physical and mental performance and how exposed we are to future risks of chronic diseases
What are amino acid supplements? What benefits do they have and how do they work? Who are they indicated for? Alessandro Orlandini, M.D., a pharmaceutical chemist and specialist in clinical biochemistry, now medical director of the Italian company Professional Dietetics, answers these questions.
When it comes to cardiovascular disease, the age of the immune system matters more than chronological age. Today the iAge “inflammatory clock” makes it possible to estimate it. How does it work?
Longevity genes can be activated with a specific mix of nutrients. This is what prompted SoLongevity research to develop a special formulation: a combination of amino acids, polydatin and NAC which, in a controlled clinical trial, proved effective in rebalancing oxidative stress and reducing inflammatory parameters.
A study published in Science identified four age-related phases of the metabolism: it is very fast in the first year of life, then slows down little by little until the age of 20, remains stable between 20 and 60, and only slows down again in later life.
They can leverage public trust and have a large presence throughout the country for easy access and proximity. This is why pharmacies are entitled to become more and more a point of reference for health: the first destination for primary care promotion
When it comes to cardiovascular disease, the age of our immune system matters more than age. Today, the iAge “inflammatory clock” allows us to estimate it. How does it work?
But is the elixir of long life – assuming it exists – to be found in our genes or in our habits? Immunologist Alberto Beretta, President and Scientific Director of SoLongevity, spoke on this topic at the summit. His research focuses in particular on the role of...
SoLongevity has appointed its new Scientific Committee, which will be joined by a new body, the Clinical Committee, with the aim of translating the indications emerging from the Scientific Committee into clinical practice and supporting the company's medical staff in...
Physical activity protects us from heart attacks and strokes, reduces the risk of diabetes, keeps neurodegenerative diseases such as Alzheimer's at bay and lowers the risk of developing tumors”, explains Alberto Beretta, immunologist and scientific director of...
As explained by Alberto Beretta, immunologist and scientific director of SoLongevity, a scientific organization that develops anti-aging strategies and anti-aging nutraceutical formulations, «molecular imbalances can begin from age 30 and produce the first...
Extending human life is a dream that has always existed, ever since people organized themselves into societies, but today's goal is not simply to extend life, but to live a long, healthy life”, says Dr. Alberto Beretta, President and Scientific Director of...
Yoga reduces systemic inflammation, a key factor in aging and chronic diseases. Yoga exercises improve the variation in the interval between one heartbeat and the next. This interval should always be irregular and never constant: during the night, in fact, the heart...
Human life can be strongly conditioned by the behaviors and external environmental factors to which we are exposed and to which we react biologically throughout our lives, and among these, the identity of the places where we live, study, work, build relationships and...
The immunologist and longevity expert Alberto Beretta, Director of the Scientific Committee of SoLongevity, explains: “The practice of yoga is associated with longevity through several scientific mechanisms. Studies have shown that yoga reduces systemic inflammation,...
The immunologist and longevity expert Alberto Beretta, director of the Scientific Committee of SoLongevity, explains: “The practice of yoga is associated with longevity through several scientific mechanisms. Studies have shown that yoga reduces systemic inflammation,...
Taking care of your skin is essential, also because it improves self-esteem and emotional well-being, which are indispensable for good health” advises Alberto Beretta, scientific director of SoLongevity. Go to the article
“The approach is not to look for blue zones or fountains of youth. Since we now know what keeps us healthy – eating well, sleeping well, exercising, staying connected with others, cultivating intellectual capital – the goal is to make it happen everywhere” Nic...
The third chapter of our guide is about the criteria for evaluating a food supplement. What “good” characteristics should it have? From certifications to bioavailability to the production chain.
In the second article of our guide to food supplementation, we offer a list of questions to figure out what you really need
The first of a series of articles to guide you into the world of dietary supplements. It starts from basic: what we should be aware of before approaching the food supplements’ shelf in pharmacies and herbalists, or in the supermarket
Obesity is one of the main risk factors for the development of severe forms of Covid-19: according to the experts, chronic inflammation and an altered immune system are involved. Just as it does when you get older.
One of our goals is to promote healthy longevity: reaching 90-95 years of age still in good shape is possible for everyone, at least in theory”. So says Alberto Beretta, president of the SoLongevity Foundation, scientific director of SoLongevity, immunologist and...
The one called Long Covid seems to be a real syndrome. Are there tests to measure its effects on the body? And what can we do to improve the symptoms? Today we publish the first of a series dedicated to the Long Covid in which we will deepen the diagnostic and therapeutic aspects, and the perspectives of research.
Called TET 1 seems to be essential to ensure the formation of new connections between neurons. A study from the Graduate Center of New York shows that as we age, its production declines. The next step is to try to stop this phenomenon.
SoLongevity is the only Italian company to join the National Innovation Center for Aging (N.I.C.A.) in the UK, one of the most advanced international realities in the world in basic and translational research on aging. Mission: to transform longevity medicine and technology into services for the general public.
At least three mechanisms are known why acute inflammation can become chronic, accelerating aging. And there are foods that can lower inflammation, but be careful of so-called “anti-inflammatory diets” that are not based on science
Sirtuins are special proteins triggered to preserve the cell life under risky environmental conditions by pausing the cell’s most wasteful activities. This mechanism can be used to counteract aging. Can the choice of certain foods help?
Ozone boosts immune defenses and is antioxidant and anti-inflammatory; cold stimulates sirtuins, the longevity genes; fasting can have an anti-aging effect if designed and personalized with care, and it is not suitable for everyone”, says Beretta, emphasizing a...
The Milan Longevity Summit aims to promote Milan as a cutting-edge international scientific center and to produce a ten-point document, the Milan Longevity Program, to help legislators, industry operators and the public at large improve the population’s lifestyle and contribute to a healthy, active and efficient old age.
What to do if NAD is in short supply? “Important help comes from the combination of cosmetics and nutraceuticals. The thin boundary between the epidermis and the dermis is the meeting point of skin longevity and that of the whole body; it is here that the two...
The over-50 population will double in importance between now and 2040, from 41,000 billion of GDP in 2020 to 82,000. Go to the article
“The goal is to move from a society of old age to one of longevity: life expectancy has increased, but we need to extend people's health. Only in this way will we weigh less on the health system and contribute by working longer.” explains Nicola Palmarini, director of...
In youth, a diet rich in calcium and vitamin D is essential for bone health” explains Hellas Cena, member of the SoLongevity scientific committee, who spoke at the Milan Longevity Summit precisely about gender nutrition with a focus on women. Go to the article
Memory and concentration issues, fogginess, anxiety, depression, and loss of taste and smell: these are all neurocognitive symptoms of what is known as Long Covid Syndrome.
According to some clinical observations, the immune system of young Covid-19 survivors appears to age prematurely, contributing to the onset of Long Covid. But this ageing process could also be reversed
The science of longevity – explains Dr. Alberto Beretta, Filorga opinion leader, immunologist and researcher, founder and scientific director of SoLongevity – has identified a large number of active ingredients capable of acting on both systemic and skin aging Go to...
Edited by Maria Teresa Lamberti. This episode discusses longevity, new frontiers for improving the aging phase, and neuroscience. Guests: Guendalina Graffigna, Full Professor of Consumer and Health Psychology at the Università Cattolica del Sacro Cuore, and Viviana...
SoLongevity's goal, through the union of researchers and clinicians, is in fact to transfer the knowledge of scientific research on cellular aging into high-level personalized medical services, pursuing its mission of inspiring tailor-made longevity medicine for the...
The biological clock is one of the most self perceived physiological mechanisms, sensitive to our lifestyle and ageing processes. An ancestral system that governs the rhythm of our body and that we must know and respect.
It only takes 15 minutes of intense physical activity to improve procedural memory. The study, published in Scientific Reports, offers new ideas for the development of strategies for the prevention of neurodegenerative diseases.
Pro-longevity nutrion demands a smart management of Glucose and Proteins metabolic level. Let’s understand which nutritional strategies are more effective and useful for an healthy ageing.
SoLongevity research to understand the action of COVID in the presence of the body’s aging processes takes a significant step forward
Understanding our metabolism to consciously nourish ourselves in order to build a long and healthy life.
The age, which depends on the date of birth, does not necessarily coincide with the real ageing of our organism, i.e. the biological age. Which can be measured with the Biological Age Score, slow it down and sometimes take it back, without resorting to drugs.
It is known as inflammaging: a state of low grade but chronic inflammation, which damages the body. Studies have shown that it plays an important role in the onset of diseases associated with ageing and in the fragility of older people.
Solongevity Research, published by the international scientific journal in Immunology, addresses the issue of interactions between SARS-CoV-2 and other seasonal coronaviruses, immunological interactions that may explain the severe clinical course of some patients and the seasonal pattern.
Using artificial intelligence and Eeg performed in sleep, a team of researchers has developed a new test to estimate the biological age of the brain and predict the risk of dementia.
A research by the University of Illinois suggests that the decline in cognitive performance in postmenopausal women depends on decreased activity of the mitochondria, the “powerhouses” of the cell.
from 30 to 60 year old, about 7.5 kg of muscle mass is lost in favour of fat mass. This is a physiological phenomenon linked to ageing, which can become pathological. In this case we speak of sarcopenia. Muscle decline, however, can be prevented.
Even the brain gets old. The loss of cognitive ability is linked to neurobiological changes, such as the thinning of the cerebral cortex. Today it is possible to measure this process and intervene both to slow it down and to recover what has been lost.
Along our lives, the genetic code contained in our cells accumulates small damages and the telomeres, the ends of the chromosomes, shorten, making it even less stable. Two phenomena linked to the ageing process and diseases of old age
As the immune system ages, it undergoes alterations and becomes less efficient. This is how processes such as immunosenescence and inflammaging affect it, exposing us to an increased risk of infection by pathogens such as the new coronavirus SARS-CoV-2.
The elderly are more susceptible to infections such as coronavirus SARS-CoV-2 due to phenomena such as immunosenescence and inflammation. At their origin, however, there are epigenetic changes that we can influence through our lifestyle.
115 years is the estimated intrinsic capacity of the human being to live. But how long we live, and how we live, does not depend solely on our genes. Epigenetic studies have shown that there are mechanisms that can repair DNA damage and increase longevity.
the whole set of organisms living in our intestines is called microbiota. Today we know that they are key for health and that they also have a role in the ageing process.
Yes, while ageing the reactions that occur in the body become less efficient. But through small interventions on nutrition and physical activity it is possible to stimulate it, stopping the aging process and reducing the risk of disease.
The genes’ role in the way we age has shrunk in recent years. Much more, in fact, depends on epigenetics, the set of biochemical reactions acting on the genome. Here is what epigenetic ageing is and what we can do to slow it down
It is known as inflammaging: a state of low grade but chronic inflammation, which damages the body. Studies have shown that it plays an important role in the onset of diseases associated with ageing and in the fragility of older people.
They are called SIRT and qualified as ” longevity genes”. They are responsible for the production of sirtuins, fundamental proteins that allow cells – and us – to live longer. Scientists have begun to understand how to make them work at their best.
An international team of researchers has identified 9 “hallmarks”: key mechanisms of the ageing process of all organisms and many diseases such as cancer, diabetes, cardiovascular and neurodegenerative diseases. The role of Epigenetics is central
The age, which depends on the date of birth, does not necessarily coincide with the real ageing of our organism, i.e. the biological age. Which can be measured with the Biological Age Score, slow it down and sometimes take it back, without resorting to drugs.
